Sleep Loss And Pain: Why Poor Sleep Makes Pain Worse

Quick Answer: Yes, poor sleep can make pain feel worse. A 2013 review says even a single night of sleep disturbance may increase pain and pain sensitivity. It also found sleep problems often come before new or worsening chronic pain. CBT for insomnia (CBT-I) improves sleep in people with pain, though its effect on pain itself is mixed.

Rate your own sleep trouble with our insomnia severity calculator.

Does Lack Of Sleep Make Pain Worse?

The research says it can. A review of recent prospective and experimental studies found that experimental disturbance of sleep, even after a single night, has the potential to increase both clinical pain and responses to pain tests. It adds that the effects may differ between healthy people and people with a pain condition (Finan et al. 2013).

In the review, 5 of 8 early experimental studies found that sleep deprivation made people more sensitive to pain, and 3 did not. The authors note those early studies had limits, such as small samples, so the picture was not settled.

Early Experiments on Sleep Loss and Pain Two bars from a 2013 review of 8 early experimental studies. 5 found that sleep deprivation increased pain sensitivity. 3 found no such effect. 8 Early Studies, Two Results More pain5 studies No effect3 studies Source: Finan et al. 2013. Bar lengths are to scale.

Text version: of 8 early experimental studies, 5 found that sleep deprivation increased pain sensitivity and 3 found no such effect (Finan et al. 2013).

Which Comes First, Poor Sleep Or Pain?

They affect each other, but sleep may have the stronger pull. The 2013 review says the prevailing view has been that sleep and pain are reciprocally related. A key trend in population studies is that sleep impairments reliably predict new cases and flare-ups of chronic pain. Studies that tracked people day by day support the idea that sleep problems predict pain better than pain predicts sleep problems.

Of 9 recent prospective studies that tested both directions, 6 found stronger evidence that sleep came first. That leaves 3 that did not, so the finding is a trend, not a rule.

Question What the Review Found
Does one bad night raise pain? It can, in experiments; effects differ by population
Do sleep problems predict new pain? Reliably, in population studies
Which direction is stronger? 6 of 9 prospective studies favored sleep first
Is the link proven causal? The authors say questions remain about direction and mechanisms

Why Might Poor Sleep Increase Pain?

The review points to the body’s own pain control. Recent experiments suggest sleep disturbance may impair key processes behind chronic pain, including endogenous pain inhibition, which is the body’s built-in way of dampening pain signals, and joint pain. It lists dopamine and opioid systems, mood, and social factors as areas for more research.

In plain terms, sleep seems to help the body turn the volume down on pain. Without enough of it, the volume stays higher, and ordinary aches may feel sharper than they would after a good night. The mechanisms are still being worked out, so no one can yet say exactly how.

The Sleep and Pain Loop Three cards. Poor sleep may weaken the body’s pain control. Pain can then make sleep harder. Reviews suggest sleep problems more often come first. The Sleep and Pain Loop 1. Poor sleepPain control isweaker 2. More painHigher pain andsensitivity 3. Worse sleepPain disruptsthe next night Source: Finan et al. 2013 review. A loop, not a proven chain.

How Common Is Poor Sleep In Chronic Pain?

Very common. A 2014 review says the majority of patients with chronic pain report poor sleep quality, and that insomnia is the most prevalent form of sleep disturbance in chronic pain. It describes insomnia and chronic pain as having a high rate of comorbidity and as reciprocally related. It gives no exact percentage, and neither did the other sources we checked (Finan et al. 2014).

The same review notes that sleep loss impairs immune function, emotion regulation and thinking, and heightens pain sensitivity. These effects can feed long-term pain problems.

What Is Insomnia, And When Is It Chronic?

NHLBI defines chronic insomnia as trouble sleeping 3 or more nights a week for more than 3 months that cannot be fully explained by another health problem. It adds that chronic insomnia raises your risk of high blood pressure, coronary heart disease, diabetes and cancer (NHLBI). If pain keeps you up that often, treat the sleep problem as its own issue.

Our insomnia guide covers the full picture.

What Do Studies Of Real Patients Show?

Several day-to-day and year-long studies point the same way. In a 1-year study of people with fibromyalgia, sleep disturbance came before increases in pain, while pain at the start was not significantly tied to sleep problems a year later. In people with jaw joint pain (temporomandibular disorder), ups and downs in insomnia severity over a month predicted next-month changes in pain, but changes in pain did not predict later insomnia. In the general population, a poor night predicted more pain the next day, and that effect was stronger than the reverse.

These are the studies behind the review’s conclusion that sleep often comes first. They do not prove cause, but they are consistent.

What About Sleep Medicines For Pain-Related Insomnia?

NHLBI lists several medicine types and urges you to talk to your doctor about benefits and side effects. Some prescription sleep medicines, such as zolpidem and eszopiclone, can rarely cause sleep activities like walking, eating or driving while asleep. Benzodiazepines may be prescribed if other treatments have not worked, but can interact dangerously with other medicines, can be habit-forming and should be taken for only a few weeks. Some medicines used for other conditions can also raise the risk of insomnia.

That matters if you take pain medicines. Always ask your provider before combining anything that affects sleep or alertness.

Does CBT-I Help When You Have Pain?

It helps sleep. It is less sure to help pain. The 2014 review looked at six randomized trials of CBT-I in people with both insomnia and chronic pain. It found CBT-I produces clinically meaningful improvements in sleep symptoms. Effects on pain are inconsistent, but tend to favor how well people function over how intense the pain is.

That is still worth having. Better sleep and better daily function can matter even when the pain score stays similar. See our overview of CBT-I.

What Does CBT-I Involve?

NHLBI describes CBT-I as a 6- to 8-week treatment plan that helps you fall asleep faster and stay asleep longer. It is usually recommended as the first option for long-term insomnia and can be very effective. A doctor, nurse or therapist can deliver it in person, by telephone or online (NHLBI treatment page). Its parts are:

  1. Cognitive therapy, which helps you feel less nervous about not being able to sleep.
  2. Relaxation or meditation, which teaches you to relax and fall asleep faster.
  3. Sleep education, which teaches good sleep habits.
  4. Sleep restriction, which sets a limited time in bed, then increases it as sleep improves.
  5. Stimulus control, which links bed with sleep: go to bed only when sleepy and get up if you cannot sleep.

If pain limits how you lie or move, tell the therapist so the plan can fit your body.

What Can You Do On Your Own?

NHLBI suggests going to sleep and waking up around the same time each day, even on weekends, and avoiding electronic devices before bed. These are general habits. Pair them with care for your pain from your own provider:

  • Keep a steady wake-up time.
  • Keep a sleep diary of bedtime, wake-ups and pain levels for a couple of weeks.
  • Tell your provider that sleep and pain seem tied together.
  • Review basics in sleep hygiene 101.

If night waking is the main issue, see waking up at night.

When To See A Doctor

Talk to a doctor if pain keeps you from sleeping most nights, your sleep trouble lasts 3 nights a week for more than 3 months, or pain and poor sleep are hurting your daily life. NHLBI says your provider may ask about your sleep habits and ask you to keep a sleep diary.

Do not stop or change pain medicines on your own, and ask before starting sleep medicines. If pain and poor sleep come with thoughts of self-harm, call or text 988 in the US.

FAQs About Sleep Loss And Pain

Can One Bad Night Of Sleep Make Pain Worse?

In experiments, even a single night of sleep disturbance has the potential to increase pain and pain sensitivity, according to a 2013 review. Effects may differ by group.

Does Pain Or Poor Sleep Come First?

The review found 6 of 9 prospective studies favored sleep coming first. Both directions likely play a part.

Does CBT-I Reduce Pain?

It improves sleep. Effects on pain are inconsistent, but tend to favor function over pain severity.

Why Does Poor Sleep Raise Pain Sensitivity?

The review points to impaired pain inhibition, the body’s built-in way of dampening pain signals, though the exact mechanisms are still being studied.

Is The Sleep And Pain Link The Same In Everyone?

Not quite. The review notes that effects may vary between healthy people and people with a clinical pain condition.

How Long Does CBT-I Take?

NHLBI describes a 6- to 8-week plan, delivered in person, by telephone or online.

What Counts As Chronic Insomnia?

Trouble sleeping 3 or more nights a week for more than 3 months, per NHLBI.

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